Add to ORKGI N 1898 Tigerstedt and Bergmann 1 discovered a pressor substance in normal kidneys to which they gave the name renin. This substance had a prolonged pressor effect when injected intravenously into animals, successive injections had a diminishing pressor action (tachyphylaxis), and it was not found in organs other than the kidneys. Their findings have been widely confirmed by subsequent investigators. With the development of a method of inducing hypertension experimentally in animals by Goldblatt, Lynch, Hanzal, and Summerville 2 and with the resultant evidence that this renal hypertension was apparently due to a humoral mechanism,3'4 the role played by renin in experimental hypertension has recently been the subject of ex-tensive stud...
Experimental studies on renovascular hypertension were made on dogs. Hypertension was successfully p...
Experimental studies on renovascular hypertension were made on dogs. Hypertension was successfully p...
SUMMARY The assessment of the possible role played by the renin-angiotensin system in maintaining ar...
ALTHOUGH it is widely believed thati renin release from the kidney is the mechanism responsible for ...
Renin was discovered by the Finnish physiologist, Robert Tigerstedt, working with his medical studen...
The advances in our knowledge of renal hypertension over the last 75 years represents outstanding ac...
Foreword: Tigerstedt and Bergman discovered in 1898 the pressure-raising substance from saline rabbi...
In 1898, Tigerstedt and Bergman published their observation that kidney extracts produce pressor eff...
The corner-stone of the Renin-Angiotensin System was laid down almost seven decades ago when Tigerst...
The history of the renin angiotensin system (RAS) began in 1898 with the studies made by Tigerstedt,...
stricted the renal arteries in dogs and pro-duced chronic arterial hypertension. Numer-ous attempts ...
• The nature of the stimulus that causes kid-neys to release renin has not been established with cer...
Increase in cardiovascular reactivity following bilateral nephrectomy has previously been found to b...
by partial constriction of their renal artery. After the constriction of renal artery, the changes ...
THE role of the kidney in experimental renal hypertension—and prob-ably also in human renal hyperten...
Experimental studies on renovascular hypertension were made on dogs. Hypertension was successfully p...
Experimental studies on renovascular hypertension were made on dogs. Hypertension was successfully p...
SUMMARY The assessment of the possible role played by the renin-angiotensin system in maintaining ar...
ALTHOUGH it is widely believed thati renin release from the kidney is the mechanism responsible for ...
Renin was discovered by the Finnish physiologist, Robert Tigerstedt, working with his medical studen...
The advances in our knowledge of renal hypertension over the last 75 years represents outstanding ac...
Foreword: Tigerstedt and Bergman discovered in 1898 the pressure-raising substance from saline rabbi...
In 1898, Tigerstedt and Bergman published their observation that kidney extracts produce pressor eff...
The corner-stone of the Renin-Angiotensin System was laid down almost seven decades ago when Tigerst...
The history of the renin angiotensin system (RAS) began in 1898 with the studies made by Tigerstedt,...
stricted the renal arteries in dogs and pro-duced chronic arterial hypertension. Numer-ous attempts ...
• The nature of the stimulus that causes kid-neys to release renin has not been established with cer...
Increase in cardiovascular reactivity following bilateral nephrectomy has previously been found to b...
by partial constriction of their renal artery. After the constriction of renal artery, the changes ...
THE role of the kidney in experimental renal hypertension—and prob-ably also in human renal hyperten...
Experimental studies on renovascular hypertension were made on dogs. Hypertension was successfully p...
Experimental studies on renovascular hypertension were made on dogs. Hypertension was successfully p...
SUMMARY The assessment of the possible role played by the renin-angiotensin system in maintaining ar...