This article explores the question whether the relationship between corporate governance and innovation is affected by the extent to which the firm is exposed to agency problems and asset specificity issues. In particular, we argue that different combinations of asset specificity and agency costs are associated to firm age and sector of activity and predict heterogenous effects of ownership concentration on innovation across different types of firms. We use a unique data set of about 35,000 Italian manufacturing corporations over the 2002–2007 period and run a hurdle model, distinguishing four subgroups of firms on the basis of their age (greater or lower than 15 years) and of whether they belong to a high-technology or low-technology secto...