Meniere's, migraine, and motion sickness

Conclusion:Elevated Motion Sickness Susceptibility (MSS) in Meniere’s disease (MD) is likely to be aconsequence of the onset of MD and not migraineperse.Objectives:Pathologies of the vestibular system influence MSS. Bilateral vestibular deficits lower MSS,vestibular neuritis or benign paroxysmal positional vertigo have little overall effect, whereas vestibularmigraine elevates MSS. However, less is known about MSS in MD, a condition in which many patientsexperience vestibular loss and migraine symptoms.Methods:The authors conducted an online survey that posed diagnostic and disease questions beforeaddressing frequency of headaches, migraines, visual display dizziness (VDD), syncope, social life, andwork impact of dizziness (SWID4) and motion sickness susceptibility (MSSQ). The two groups were:diagnosed MD individuals with hearing loss (n¼751) and non-MD individuals in the control group(n¼400).Results:The MD group showed significantly elevated MSS, more headache and migraine, increasedVDD, higher SWID4 scores, and increased syncope. MSS was higher in MD than controls only after thedevelopment of MD, but not before, nor in childhood. Although elevated in MD compared with con-trols, MSS was lower than migraine patients from past data. Multivariate analysis revealed VDD, SWID4,and MSS in adulthood as the strongest predictors of MD, but not headache nor migraine