The Association of Multiple Biomarkers of Iron Metabolism and Type 2 Diabetes: The EPIC-InterAct Study.
- Podmore, Clara
- Meidtner, Karina
- Schulze, Matthias B
- Scott, Robert A
- Ramond, Anna
- Butterworth, Adam S
- Di Angelantonio, Emanuele
- Danesh, John
- Arriola, Larraitz
- Barricarte, Aurelio
- Boeing, Heiner
- Clavel-Chapelon, Françoise
- Cross, Amanda J
- Dahm, Christina C
- Fagherazzi, Guy
- Franks, Paul
- Gavrila, Diana
- Grioni, Sara
- Gunter, Marc J
- Gusto, Gaelle
- Jakszyn, Paula
- Katzke, Verena
- Key, Timothy J
- Kühn, Tilman
- Mattiello, Amalia
- Nilsson, Peter
- Olsen, Anja
- Overvad, Kim
- Palli, Domenico
- Quirós, J Ramón
- Rolandsson, Olov
- Sacerdote, Carlotta
- Sánchez-Cantalejo, Emilio
- Slimani, Nadia
- Sluijs, Ivonne
- Spijkerman, Annemieke M W
- Tjonneland, Anne
- Tumino, Rosario
- van der A, Daphne L
- van der Schouw, Yvonne T
- Feskens, Edith J M
- Forouhi, Nita G
- Sharp, Stephen J
- Riboli, Elio
- Langenberg, Claudia
- Wareham, Nicholas J
DOIAbstract
Observational studies show an association between ferritin and type 2 diabetes (T2D), suggesting a role of high iron stores in T2D development. However, ferritin is influenced by factors other than iron stores, which is less the case for other biomarkers of iron metabolism. We investigate associations of ferritin, transferrin saturation (TSAT), serum iron, and transferrin with T2D incidence to clarify the role of iron in the pathogenesis of T2D
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