AbstractWhile p53 family members have distinct nonoverlapping functions, the involvement of p63 and p73 in p53-mediated apoptosis is controversial. Results of a recent study indicate that at least in thymocytes, p53-dependent apoptosis occurs independently of p63 and p73
AbstractRecently, p73 was identified as a structural and functional homolog of p53. The p73 protein ...
The transcription factor and tumour suppressor p53 and its two homologues p63 and p73 form a family ...
poster abstractTumor protein p53 is the most commonly mutated tumor suppressor in human cancers. The...
AbstractWhile p53 family members have distinct nonoverlapping functions, the involvement of p63 and ...
AbstractThe p53 tumor suppressor acts as a transcription factor and has a central function in contro...
p73 and p63 are two homologs of the tumor suppressive transcription factor p53. Given the high degre...
Summaryp63 and p73 are functionally and structurally related to the tumor suppressor p53. However, t...
The p53 gene is the most frequently mutated gene in human cancer. The identification of two homologu...
The p53 tumor suppressor gene is the most frequent target for genetic alterations in human cancers, ...
AbstractDespite the common assumption that p53 by itself can induce apoptosis, results of a recent s...
The tumor suppressor p53 and its oncogenic sibling p63 (ΔNp63) direct opposing fates in tumor develo...
p53 is the most frequently inactivated tumor suppressor gene in human cancer, whereas its homologue,...
All known members of the p53 gene family, including the two homologs p73 and p63, have multiple biol...
AbstractTP53 belongs to a small gene family that includes, in mammals, two additional paralogs, TP63...
AbstractMost chemotherapeutic agents induce DNA damage, leading to p53 accumulation and apoptosis. T...
AbstractRecently, p73 was identified as a structural and functional homolog of p53. The p73 protein ...
The transcription factor and tumour suppressor p53 and its two homologues p63 and p73 form a family ...
poster abstractTumor protein p53 is the most commonly mutated tumor suppressor in human cancers. The...
AbstractWhile p53 family members have distinct nonoverlapping functions, the involvement of p63 and ...
AbstractThe p53 tumor suppressor acts as a transcription factor and has a central function in contro...
p73 and p63 are two homologs of the tumor suppressive transcription factor p53. Given the high degre...
Summaryp63 and p73 are functionally and structurally related to the tumor suppressor p53. However, t...
The p53 gene is the most frequently mutated gene in human cancer. The identification of two homologu...
The p53 tumor suppressor gene is the most frequent target for genetic alterations in human cancers, ...
AbstractDespite the common assumption that p53 by itself can induce apoptosis, results of a recent s...
The tumor suppressor p53 and its oncogenic sibling p63 (ΔNp63) direct opposing fates in tumor develo...
p53 is the most frequently inactivated tumor suppressor gene in human cancer, whereas its homologue,...
All known members of the p53 gene family, including the two homologs p73 and p63, have multiple biol...
AbstractTP53 belongs to a small gene family that includes, in mammals, two additional paralogs, TP63...
AbstractMost chemotherapeutic agents induce DNA damage, leading to p53 accumulation and apoptosis. T...
AbstractRecently, p73 was identified as a structural and functional homolog of p53. The p73 protein ...
The transcription factor and tumour suppressor p53 and its two homologues p63 and p73 form a family ...
poster abstractTumor protein p53 is the most commonly mutated tumor suppressor in human cancers. The...