In this issue of Cell, Guenther et al. (2007) analyze the presence of chromatin marks and RNA polymerase at transcription start sites in the human genome. Their results reveal that many “inactive” genes harbor histone marks associated with active transcription at their 5′ ends and that although these genes initiate transcription, they do not generate full-length transcripts
Destruction of intact cellular proteins is largely orchestrated by ATP-dependent ubiquitination and ...
In this issue of Cell, Grosschedl and colleagues (Dobreva et al., 2006) report that the nuclear matr...
The complexity of genomic aberrations in most human tumors hampers delineation of the genes that dri...
In a recent paper in PNAS, Rigoutsos et al. (2006) describe a nonrandom pattern of repeated elements...
The nuclear protein kinase ATR is a key regulator of genome integrity that functions at checkpoints ...
In this issue of Cell, Axel and colleagues (Lomvardas et al., 2006) report that a single enhancer of...
Linker histones of the H1 family are among the most abundant components of chromatin. In this issue ...
The PML protein induces senescence, and, upon oncogenic stress, its absence promotes cellular transf...
The pattern of histone modifications, called the histone code, influences transitions between chroma...
Genomic imprinting is an essential epigenetic process that controls the size of seeds in flowering p...
Limitations on a differentiated cell's pluripotency can be erased by nuclear transfer or by fusion w...
Meiosis includes a reductional division in which homologous chromosomes, rather than sister chromati...
SummaryMicroorganisms growing on surfaces can form biofilms under certain conditions. In this issue ...
Fish and amphibian hearts are known to regenerate after partial resection, but the molecular mechani...
Mutations in the gene encoding otoferlin are known to cause deafness, but the mechanism is unclear. ...
Destruction of intact cellular proteins is largely orchestrated by ATP-dependent ubiquitination and ...
In this issue of Cell, Grosschedl and colleagues (Dobreva et al., 2006) report that the nuclear matr...
The complexity of genomic aberrations in most human tumors hampers delineation of the genes that dri...
In a recent paper in PNAS, Rigoutsos et al. (2006) describe a nonrandom pattern of repeated elements...
The nuclear protein kinase ATR is a key regulator of genome integrity that functions at checkpoints ...
In this issue of Cell, Axel and colleagues (Lomvardas et al., 2006) report that a single enhancer of...
Linker histones of the H1 family are among the most abundant components of chromatin. In this issue ...
The PML protein induces senescence, and, upon oncogenic stress, its absence promotes cellular transf...
The pattern of histone modifications, called the histone code, influences transitions between chroma...
Genomic imprinting is an essential epigenetic process that controls the size of seeds in flowering p...
Limitations on a differentiated cell's pluripotency can be erased by nuclear transfer or by fusion w...
Meiosis includes a reductional division in which homologous chromosomes, rather than sister chromati...
SummaryMicroorganisms growing on surfaces can form biofilms under certain conditions. In this issue ...
Fish and amphibian hearts are known to regenerate after partial resection, but the molecular mechani...
Mutations in the gene encoding otoferlin are known to cause deafness, but the mechanism is unclear. ...
Destruction of intact cellular proteins is largely orchestrated by ATP-dependent ubiquitination and ...
In this issue of Cell, Grosschedl and colleagues (Dobreva et al., 2006) report that the nuclear matr...
The complexity of genomic aberrations in most human tumors hampers delineation of the genes that dri...
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