AbstractA graph is connected-homogeneous if any isomorphism between finite connected induced subgraphs extends to an automorphism of the graph. In this paper we classify the countably infinite connected-homogeneous graphs. We prove that if Γ is connected countably infinite and connected-homogeneous then Γ is isomorphic to one of: Lachlan and Woodrow's ultrahomogeneous graphs; the generic bipartite graph; the bipartite ‘complement of a complete matching’; the line graph of the complete bipartite graph Kℵ0,ℵ0; or one of the ‘treelike’ distance-transitive graphs Xκ1,κ2 where κ1,κ2∈N∪{ℵ0}. It then follows that an arbitrary countably infinite connected-homogeneous graph is a disjoint union of a finite or countable number of disjoint copies of on...