Research of poisonings with psychotropic drug mixtures by thin-layer chromatography

It is observed increase in number of remedy intoxications in Lithuania, especially important is intoxication with psychotropic drugs and their mixtures. The thin-layer chromatography (TLC) method was proposed for separation and identification of drugs in mixture aminazine: nitrazepam : barbamylum. The mixture of these drugs excreted from body fluids (blood and urine) was investigated by TLC. Most acceptable these mobile phases : 1. Diethyl ether: dioxane \u96 40:60. Rf values for drugs: aminazine 0.23\u960.25; barbamylum 0.85\u960.9; nitrazepam 0.75\u960.8. 2. Diethyl ether: NH3 (25%): benzenum \u96 80:10:10. Rf values for drugs: aminazine 0.55\u960.58; barbamylum 0.32\u960.35; nitrazepam 0.17\u960.2