Nanosurfaces Scaffold and Magnetic Nanoparticles to Direct the Neuronal Growth Process: Future Strategies for Peripheral Nerve Regeneration

Peripheral nerves injuries are common lesions than often cause loss of function and poor outcome. Current strategies to nerve repair take advantage by microsurgical suture. In case of severe nerve gap (>50mm),the gold standard remains the autologous graft. Recently, researchers focused on two main areas of investigation: the role of the interaction between cells with the extracellular membrane (ECM )and the forces acting during axonal elongation