Comprehensive analysis and characterization of the human salivary proteome is an important step towards the possible use of saliva for diagnostic and prognostic purposes. The contribution of the different sources to whole saliva, and the evaluation of individual variability and physiological modifications have been investigated by top-down proteomic approaches, disclosing the faceted and complex profile of the human salivary proteome. All this information is essential to develop saliva protein biomarkers. In this Review the major results obtained in the field by top-down platforms, and the improvements required to allow a more complete picture, will be discussed
Proteomic platforms can be classified in bottom-up strategies, which analyze the sample after proteo...
Proteomic platforms can be classified in bottom-up strategies, which analyze the sample after proteo...
Proteomic platforms can be classified in bottom-up strategies, which analyze the sample after proteo...
Comprehensive analysis and characterization of the human salivary proteome is an important step towa...
Comprehensive analysis and characterization of the human salivary proteome is an important step towa...
Comprehensive analysis and characterization of the human salivary proteome is an important step towa...
The development of new separation techniques and different mass spectrometry instrumental devices, a...
The development of new separation techniques and different mass spectrometry instrumental devices, a...
The development of new separation techniques and different mass spectrometry instrumental devices, a...
The development of new separation techniques and different mass spectrometry instrumental devices, a...
The development of new separation techniques and different mass spectrometry instrumental devices, a...
Human saliva harbours proteins of clinical relevance and about 30% of blood proteins are also presen...
The salivary proteome is a complex protein mixture resulting from the activity of salivary glands w...
Human saliva harbours proteins of clinical relevance and about 30% of blood proteins are also presen...
The salivary proteome is a complex protein mixture resulting from the activity of salivary glands w...
Proteomic platforms can be classified in bottom-up strategies, which analyze the sample after proteo...
Proteomic platforms can be classified in bottom-up strategies, which analyze the sample after proteo...
Proteomic platforms can be classified in bottom-up strategies, which analyze the sample after proteo...
Comprehensive analysis and characterization of the human salivary proteome is an important step towa...
Comprehensive analysis and characterization of the human salivary proteome is an important step towa...
Comprehensive analysis and characterization of the human salivary proteome is an important step towa...
The development of new separation techniques and different mass spectrometry instrumental devices, a...
The development of new separation techniques and different mass spectrometry instrumental devices, a...
The development of new separation techniques and different mass spectrometry instrumental devices, a...
The development of new separation techniques and different mass spectrometry instrumental devices, a...
The development of new separation techniques and different mass spectrometry instrumental devices, a...
Human saliva harbours proteins of clinical relevance and about 30% of blood proteins are also presen...
The salivary proteome is a complex protein mixture resulting from the activity of salivary glands w...
Human saliva harbours proteins of clinical relevance and about 30% of blood proteins are also presen...
The salivary proteome is a complex protein mixture resulting from the activity of salivary glands w...
Proteomic platforms can be classified in bottom-up strategies, which analyze the sample after proteo...
Proteomic platforms can be classified in bottom-up strategies, which analyze the sample after proteo...
Proteomic platforms can be classified in bottom-up strategies, which analyze the sample after proteo...