Calibration over natural targets is a very powerful way to derive the in-flight calibration of sensors (e.g., PARASOL, Vegetation, Pleiades) or if not, to validate the calibration derived using on-board devices (e.g., MODIS, MERIS). Various type of targets can be considered among oceanic sites (Rayleigh scattering, sunglint), atmospheric targets (deep convective clouds), terrestrial sites (desert, snow), or extra-terrestrial targets (moon, stars). Pseudo-invariant calibration sites (so-called PICS) are used for a very long while for many sensors because of their suitable properties in term of stability, moderated bidirectional variations, accessibility in term of cloudiness. Calibration approaches over PICS directly compare top-of-atmospher...