VSV infections that exit the early phase of infection earlier with more mRNA present produce more virions.

(A) 1000 stochastic simulations of wild-type VSV showing the number of virions produced over time. (B-F) Left: Kernel density estimate (KDE) plots of the number of virions produced vs. the time until the early phase ends. Right: KDE plots of the quantity of each mRNA species present when the early phase ends, along with the 99% CI line of best fit, for variants (B) NMGPL, (C) NGMPL, (D) NMPGL, (E) NPMGL (wild-type), and (F) NGPML. All mRNA species show a weakly positive correlation (0.2 < r < .39) with the number of virions produced, except for mL which has a very weak correlation (0 < r < .19) in all variants.