Quantification of flow cytometry analysis on inflammatory cell recruitment following HMPV TN/94-49 and C2-202 infection in a time-course experiment. The number of total recovered cells (a), dendritic cells (b), alveolar macrophages (c), and interstitial macrophages (d) for each time point were shown as mean ±SD from three mice per group. The control group sample were collected at day 5 post infection. The percentage of marker-positive cells in total cells and mean fluorescent intensity (MFI) of MHC-II (e,f) and CD11b (g,h) were also shown as mean ±SD as above. * P0.05, t-test with correction for multiple comparisons. (TIF)</p
Enocytes were used as negative control. (B) BALB/c mice were either uninfected or infected with rMVA...
<p>The plots depict reduced activation of H37RV/ARPC4 infected macrophages. <b>a)</b> Percentage of...
<p>Shown are CD45+ cells that are: A.) CD3+, B.) CD4+, and C.) Mac1+, respectively. The observed red...
<p>TLR4<sup>−/−</sup> and WT mice were either infected with hMPV or mock-infected, and sacrificed at...
<p>TLR4<sup>−/−</sup> and WT mice were mock- or hMPV-infected, and sacrificed at week 1 and 2 p.i. t...
(a) Culture scheme of murine bone marrow-derived macrophages (BMDMs). (b) Immunofluorescent assay on...
(A) HMPV pathogenic strains induced higher pro-inflammatory cytokines. C57BL/6 mice were infected wi...
<p>(<b>A</b>) BALB/c mice (<i>n</i> = 5) were infected i.n. with 5 × 10<sup>3</sup> PFU of the purif...
AbstractRecent in vivo studies suggest that hMPV is a poor inducer of inflammatory cytokines and tha...
THP-1 cells were differenciated into macrophages using PMA (100 ng/ml) before treatment with 10 μM o...
<p>(A) HMPV infected BEAS-2B cells at 18 or 24 h.p.i., were fixed and processed for immunofluorescen...
<p>Macrophages were depleted or not and mice were infected. Twenty-four hours post-primary infection...
<p>DC subsets were isolated and incubated with hMPV or media for 40 hours. Cytokine and chemokine le...
<p>Spleen mononuclear cells (SMC) were extracted on consecutive days from single and co-infected mic...
Enocytes were used as negative control. (B) BALB/c mice were either uninfected or infected with rMVA...
Enocytes were used as negative control. (B) BALB/c mice were either uninfected or infected with rMVA...
<p>The plots depict reduced activation of H37RV/ARPC4 infected macrophages. <b>a)</b> Percentage of...
<p>Shown are CD45+ cells that are: A.) CD3+, B.) CD4+, and C.) Mac1+, respectively. The observed red...
<p>TLR4<sup>−/−</sup> and WT mice were either infected with hMPV or mock-infected, and sacrificed at...
<p>TLR4<sup>−/−</sup> and WT mice were mock- or hMPV-infected, and sacrificed at week 1 and 2 p.i. t...
(a) Culture scheme of murine bone marrow-derived macrophages (BMDMs). (b) Immunofluorescent assay on...
(A) HMPV pathogenic strains induced higher pro-inflammatory cytokines. C57BL/6 mice were infected wi...
<p>(<b>A</b>) BALB/c mice (<i>n</i> = 5) were infected i.n. with 5 × 10<sup>3</sup> PFU of the purif...
AbstractRecent in vivo studies suggest that hMPV is a poor inducer of inflammatory cytokines and tha...
THP-1 cells were differenciated into macrophages using PMA (100 ng/ml) before treatment with 10 μM o...
<p>(A) HMPV infected BEAS-2B cells at 18 or 24 h.p.i., were fixed and processed for immunofluorescen...
<p>Macrophages were depleted or not and mice were infected. Twenty-four hours post-primary infection...
<p>DC subsets were isolated and incubated with hMPV or media for 40 hours. Cytokine and chemokine le...
<p>Spleen mononuclear cells (SMC) were extracted on consecutive days from single and co-infected mic...
Enocytes were used as negative control. (B) BALB/c mice were either uninfected or infected with rMVA...
Enocytes were used as negative control. (B) BALB/c mice were either uninfected or infected with rMVA...
<p>The plots depict reduced activation of H37RV/ARPC4 infected macrophages. <b>a)</b> Percentage of...
<p>Shown are CD45+ cells that are: A.) CD3+, B.) CD4+, and C.) Mac1+, respectively. The observed red...