WT B6, IFNAR KO, and STAT-KO mice were infected with 2.5 x 105 of C2-202, euthanized on day 5, and lung homogenate cytokines were measured by ELISA. (TIF)</p
<p><b>(A)</b> KC, <b>(B)</b> TNF-α and <b>(C)</b> IFNγ. Pro-inflammatory cytokine levels in wild-typ...
<p>WT and <i>Ifnar1</i><sup>-/-</sup> mice were infected intranasally (5 x 10<sup>4</sup> CFU of <i>...
(A-G; black = B6; green = IFITKO mice) B6 and IFITKO mice were infected with CVB3 (104 pfu/mouse, i....
WT, IFNAR KO, and Ifnlr-/- (IFNLR KO) mice were infected with 2.5 x 105 of C2-202 and weighed daily....
(A) Relative expression of IFNα1, IFNβ, IFNγ, and IFNλ3 mRNA in mouse lung at 1 day post-infection. ...
<p>A) WT C57Bl/6J and <i>Ifnar</i><sup>-/-</sup> mice were infected with 10<sup>8</sup> cfu of 502A ...
(A) Experimental design for IFNAR blockade. (B) Weight change and (C) day 5 lung virus titer of mice...
<p>(a) Lung tissues from the same infected mice used for the original gene expression analysis were ...
<p>Mice were administered <i>B.anthracis</i> 10<sup>8</sup> spores/mouse+IFN-γ (1 µg/ml), IFN-α (10<...
<p>BMDCs from 7–9-week-old NOD and SR-A<sup>−/−</sup> NOD mice were stimulated with poly(I∶C) (0, 10...
<p>AG129 mice were ip. infected with 10<sup>7</sup> or 10<sup>4</sup> PFU of D2Y98P, bled at the ind...
<p>(A) WT (littermate controls), β6 KO, IFNAR KO, or β6/IFNAR KO mice were intranasally inoculated w...
<p><b>(A)</b> CXCL1, <b>(B)</b> G-CSF, and <b>(C)</b> IL-12p40 concentrations (pg/mL) in bronchoalve...
<p><b>(A)</b> Flt3 ligand-derived DCs from WT and <i>Ifnar1</i><sup><i>-/-</i></sup> mice were infec...
<p>IFN-β concentrations in lung homogenate supernatants were measured by ELISA. Points represent ind...
<p><b>(A)</b> KC, <b>(B)</b> TNF-α and <b>(C)</b> IFNγ. Pro-inflammatory cytokine levels in wild-typ...
<p>WT and <i>Ifnar1</i><sup>-/-</sup> mice were infected intranasally (5 x 10<sup>4</sup> CFU of <i>...
(A-G; black = B6; green = IFITKO mice) B6 and IFITKO mice were infected with CVB3 (104 pfu/mouse, i....
WT, IFNAR KO, and Ifnlr-/- (IFNLR KO) mice were infected with 2.5 x 105 of C2-202 and weighed daily....
(A) Relative expression of IFNα1, IFNβ, IFNγ, and IFNλ3 mRNA in mouse lung at 1 day post-infection. ...
<p>A) WT C57Bl/6J and <i>Ifnar</i><sup>-/-</sup> mice were infected with 10<sup>8</sup> cfu of 502A ...
(A) Experimental design for IFNAR blockade. (B) Weight change and (C) day 5 lung virus titer of mice...
<p>(a) Lung tissues from the same infected mice used for the original gene expression analysis were ...
<p>Mice were administered <i>B.anthracis</i> 10<sup>8</sup> spores/mouse+IFN-γ (1 µg/ml), IFN-α (10<...
<p>BMDCs from 7–9-week-old NOD and SR-A<sup>−/−</sup> NOD mice were stimulated with poly(I∶C) (0, 10...
<p>AG129 mice were ip. infected with 10<sup>7</sup> or 10<sup>4</sup> PFU of D2Y98P, bled at the ind...
<p>(A) WT (littermate controls), β6 KO, IFNAR KO, or β6/IFNAR KO mice were intranasally inoculated w...
<p><b>(A)</b> CXCL1, <b>(B)</b> G-CSF, and <b>(C)</b> IL-12p40 concentrations (pg/mL) in bronchoalve...
<p><b>(A)</b> Flt3 ligand-derived DCs from WT and <i>Ifnar1</i><sup><i>-/-</i></sup> mice were infec...
<p>IFN-β concentrations in lung homogenate supernatants were measured by ELISA. Points represent ind...
<p><b>(A)</b> KC, <b>(B)</b> TNF-α and <b>(C)</b> IFNγ. Pro-inflammatory cytokine levels in wild-typ...
<p>WT and <i>Ifnar1</i><sup>-/-</sup> mice were infected intranasally (5 x 10<sup>4</sup> CFU of <i>...
(A-G; black = B6; green = IFITKO mice) B6 and IFITKO mice were infected with CVB3 (104 pfu/mouse, i....