Additional file 1 of Comparison of the efficacy of anti-diabetic medications as add-on to metformin in type 2 diabetes mellitus from a real-world database

Additional file 1: Table S1. Descriptive statistics for each drug and dose amount at index date in each cohort. Table S2. Summary of parameter estimates in MMRM with unadjusted analysis. Table S3. Baseline characteristics in each cohort: sensitivity analysis for ≥90 days between index date-1 and index date-2 in combination therapy cohort. Table S4. Descriptive summary of observed HbA1c value at 4 months with unadjusted population who had HbA1c value at 4 months. Figure S1. Plot of MMRM for difference of change from baseline in HbA1c at 4 months between cohorts with unadjusted analysis (a), PSM-adjusted analysis (b) and IPTW-adjusted analysis (c): Sensitivity analysis for patients with ≥90 days between index date-1 and index date-2 in combination therapy cohort