Co-expression analysis of differentially expressed genes.

(A) Heatmap showing the expression of the top 18 differentially expressed genes for each cell cluster (q < 0.05). (B) Differential genes (DEGs) of six major cell types between groups RespD376 and ARD614. Colors discriminate DEGs with upregulation (red) or downregulation (blue) expression. The Y-axis represents the log2-fold change of DEGs. (C) Number of DEGs between RespD376 and ARD614 in each cell type. Colors discriminate upregulation (red) or downregulation (blue) expression. (D) Heatmap showed the average expression of module hub genes in different cell types and time points. (E) The dot plot showed the pathways enriched in specificity in the five modules.