Additional gene expression comparisons.

(a) Boxplots show log2-transformed fold changes (LFC) of gene expression on glucose (instead of maltose, as in Fig 4) in evolved haploids compared to the wild-type strain for genes on aneuploid ChrXV (n = 370) and subtelomeric genes (n = 200). (b) Boxplots show LFCs of gene expression in maltose compared to glucose for ChrXV genes in each evolved haploid. Whiskers extend to 1.5× the interquartile range. Lines connect the y-axis coordinates of the same gene in each evolved isolate; axes are scaled such that an occasional outlier is truncated from the plot space for a single strain. AGT1 expression is plotted as red dots and lines, and black dashed lines indicate the null expectation for expression values between strains (a) or equivalent expression between conditions (b). The data underlying this figure can be found in S1 Data. (TIF)