Each genetic predictor (x-axis; sorted by effect size) participates in a number of reactions that might involve biomass precursors (y-axis). We here show the mean consumption (red circles) or production (blue circles) across the entire population (104 individuals). Circle sizes are proportional to the absolute value of the mean contribution relative to the biomass consumption. (TIF)</p
A: We calculate the growth rates of a fixed population in 103 random environments (represented with ...
<p>The distribution of the number of core COGs (A) and total pan-genome COGs (B) found upon sequenti...
<p>Using both per RIL CV and average for the 559 metabolites where CV could be measured, we estimate...
A: Manhattan-like plot showing the effect sizes (y-axis) of genes grouped by yeast metabolic subsyst...
A: The precursors in metabolic reconstructions are metabolites that ultimately fuel the biomass reac...
A: Fluxes that are accessible in the population, i.e. maximal bounds (vertical black lines) and rang...
A: Pleiotropy indicates the number of biomass precursors affected by a mutation of a given gene. Onl...
A: The range of flux potentially available in three reactions is represented by the white bars (from...
<p>We show the optimized biomass production of each species on <i>G</i> nutrients, for species in th...
<p>Each row represents a phenotype and consists of three cells, representing (a) model predictions b...
<p>In A) larger circles represent higher biomass (dry weight) and fecundity (eggs per female) on log...
<p>Circles are members of the optimized set of model parameters. Circle color represents the H:B (<i...
A: Probability density function estimate (kernel, bw = 0.3) of relative gene dosages of 10 populatio...
<p>Biomass is defined as the product of carrying capacity by cell size. Each point corresponds to th...
The biomass reaction involves 43 precursor metabolites (x-axis) but with stoichiometric coefficients...
A: We calculate the growth rates of a fixed population in 103 random environments (represented with ...
<p>The distribution of the number of core COGs (A) and total pan-genome COGs (B) found upon sequenti...
<p>Using both per RIL CV and average for the 559 metabolites where CV could be measured, we estimate...
A: Manhattan-like plot showing the effect sizes (y-axis) of genes grouped by yeast metabolic subsyst...
A: The precursors in metabolic reconstructions are metabolites that ultimately fuel the biomass reac...
A: Fluxes that are accessible in the population, i.e. maximal bounds (vertical black lines) and rang...
A: Pleiotropy indicates the number of biomass precursors affected by a mutation of a given gene. Onl...
A: The range of flux potentially available in three reactions is represented by the white bars (from...
<p>We show the optimized biomass production of each species on <i>G</i> nutrients, for species in th...
<p>Each row represents a phenotype and consists of three cells, representing (a) model predictions b...
<p>In A) larger circles represent higher biomass (dry weight) and fecundity (eggs per female) on log...
<p>Circles are members of the optimized set of model parameters. Circle color represents the H:B (<i...
A: Probability density function estimate (kernel, bw = 0.3) of relative gene dosages of 10 populatio...
<p>Biomass is defined as the product of carrying capacity by cell size. Each point corresponds to th...
The biomass reaction involves 43 precursor metabolites (x-axis) but with stoichiometric coefficients...
A: We calculate the growth rates of a fixed population in 103 random environments (represented with ...
<p>The distribution of the number of core COGs (A) and total pan-genome COGs (B) found upon sequenti...
<p>Using both per RIL CV and average for the 559 metabolites where CV could be measured, we estimate...