Recent advances in mouse genomics have revealed considerable variation in the form of single-nucleotide polymorphisms (SNPs) among common inbred strains. This has made it possible to characterize closely related strains and to identify genes that differ; such genes may be causal for quantitative phenotypes. The mouse strains DBA/1J and DBA/2J differ by just 5.6% at the SNP level. These strains exhibit differences in a number of metabolic and lipid phenotypes, such as plasma levels of triglycerides (TGs) and HDL. A cross between these strains revealed multiple quantitative trait loci (QTLs) in 294 progeny. We identified significant TG QTLs on chromosomes (Chrs) 1, 2, 3, 4, 8, 9, 10, 11, 12, 13, 14, 16, and 19, and significant HDL QTLs on Chr...
An F(2) pedigree based on the mouse lines DU6i and DBA/2 with extremely different growth and obesity...
Plasma high-density lipoprotein cholesterol (HDL-C) concentrations are genetically determined to a g...
OBJECTIVE: To identify the gene responsible for the quantitative trait locus (QTL) Hdlq14, a high-de...
Recent advances in mouse genomics have revealed considerable variation in the form of single-nucleot...
Recent advances in mouse genomics have revealed considerable variation in the form of single-nucleot...
Recent advances in mouse genomics have revealed considerable variation in the form of single-nucleot...
To identify genes controlling plasma HDL and triglyceride levels, quantitative trait locus (QTL) ana...
To identify genetic loci influencing lipid levels, we performed quantitative trait loci (QTL) analys...
To investigate genetic contributions to individual variations of lipoprotein cholesterol concentrati...
The NZB/B1NJ (NZB) mouse strain exhibits high cholesterol and HDL levels in blood compared with seve...
To identify additional loci that influence lipoprotein cholesterol levels, we performed quantitative...
To identify additional loci that influence lipoprotein cholesterol levels, we performed quantitative...
A higher incidence of coronary artery disease is associated with a lower level of HDL-cholesterol. W...
To investigate the quantitative trait loci (QTL) regulating plasma cholesterol, the female progeny o...
To identify genetic determinants of lipoprotein levels, we are performing quantitative trait locus (...
An F(2) pedigree based on the mouse lines DU6i and DBA/2 with extremely different growth and obesity...
Plasma high-density lipoprotein cholesterol (HDL-C) concentrations are genetically determined to a g...
OBJECTIVE: To identify the gene responsible for the quantitative trait locus (QTL) Hdlq14, a high-de...
Recent advances in mouse genomics have revealed considerable variation in the form of single-nucleot...
Recent advances in mouse genomics have revealed considerable variation in the form of single-nucleot...
Recent advances in mouse genomics have revealed considerable variation in the form of single-nucleot...
To identify genes controlling plasma HDL and triglyceride levels, quantitative trait locus (QTL) ana...
To identify genetic loci influencing lipid levels, we performed quantitative trait loci (QTL) analys...
To investigate genetic contributions to individual variations of lipoprotein cholesterol concentrati...
The NZB/B1NJ (NZB) mouse strain exhibits high cholesterol and HDL levels in blood compared with seve...
To identify additional loci that influence lipoprotein cholesterol levels, we performed quantitative...
To identify additional loci that influence lipoprotein cholesterol levels, we performed quantitative...
A higher incidence of coronary artery disease is associated with a lower level of HDL-cholesterol. W...
To investigate the quantitative trait loci (QTL) regulating plasma cholesterol, the female progeny o...
To identify genetic determinants of lipoprotein levels, we are performing quantitative trait locus (...
An F(2) pedigree based on the mouse lines DU6i and DBA/2 with extremely different growth and obesity...
Plasma high-density lipoprotein cholesterol (HDL-C) concentrations are genetically determined to a g...
OBJECTIVE: To identify the gene responsible for the quantitative trait locus (QTL) Hdlq14, a high-de...