In 2020, the UK government funded a portfolio of platform trials to develop new treatments for COVID-19. A key feature was the independent prioritization of candidate drugs with central coordination to prevent duplication, accelerating recruitment to deliver definitive trial results. A similar approach could be used for non-communicable diseases where treatment advances have been limited
OBJECTIVES: To determine if a specific immunomodulatory intervention reduces progression of COVID-19...
Background There is an urgent unmet clinical need for the identification of novel therapeutics for ...
Objectives To characterise current COVID-19-related research activities.Design Cross-sectional analy...
In 2020, the UK government funded a portfolio of platform trials to develop new treatments for COVID...
In our 2020 consensus paper, we devised ten recommendations for conducting Complex Innovative Design...
The Randomised Evaluation of COVID-19 Therapy (RECOVERY) Trial was set up in March 2020 to evaluate ...
Funder: UKRIAbstract: Objectives: Stage 1: To evaluate the safety and efficacy of candidate agents a...
Objectives Stage 1: To evaluate the safety and efficacy of candidate agents as add-on therapies to s...
The rapid global spread and significant mortality associated with the coronavirus disease (COVID-19)...
Background: Many available medicines have been evaluated as potential repurposed treatments for coro...
BackgroundAn urgent need exists to rapidly screen potential therapeutics for severe COVID-19 or othe...
Corona Virus Disease (COVID-19) drugs are not being developed at the pace in which the disease is sp...
Clinical question: What is the role of drugs in the treatment of patients with covid-19?New recommen...
The coronavirus (SARS-CoV-2) emerged in December 2019 in Wuhan, China and by the end of April 2020, ...
The latest pandemic, coronavirus disease-2019 (COVID-19), is associated with high prevalence and eas...
OBJECTIVES: To determine if a specific immunomodulatory intervention reduces progression of COVID-19...
Background There is an urgent unmet clinical need for the identification of novel therapeutics for ...
Objectives To characterise current COVID-19-related research activities.Design Cross-sectional analy...
In 2020, the UK government funded a portfolio of platform trials to develop new treatments for COVID...
In our 2020 consensus paper, we devised ten recommendations for conducting Complex Innovative Design...
The Randomised Evaluation of COVID-19 Therapy (RECOVERY) Trial was set up in March 2020 to evaluate ...
Funder: UKRIAbstract: Objectives: Stage 1: To evaluate the safety and efficacy of candidate agents a...
Objectives Stage 1: To evaluate the safety and efficacy of candidate agents as add-on therapies to s...
The rapid global spread and significant mortality associated with the coronavirus disease (COVID-19)...
Background: Many available medicines have been evaluated as potential repurposed treatments for coro...
BackgroundAn urgent need exists to rapidly screen potential therapeutics for severe COVID-19 or othe...
Corona Virus Disease (COVID-19) drugs are not being developed at the pace in which the disease is sp...
Clinical question: What is the role of drugs in the treatment of patients with covid-19?New recommen...
The coronavirus (SARS-CoV-2) emerged in December 2019 in Wuhan, China and by the end of April 2020, ...
The latest pandemic, coronavirus disease-2019 (COVID-19), is associated with high prevalence and eas...
OBJECTIVES: To determine if a specific immunomodulatory intervention reduces progression of COVID-19...
Background There is an urgent unmet clinical need for the identification of novel therapeutics for ...
Objectives To characterise current COVID-19-related research activities.Design Cross-sectional analy...