Scour constitutes a significant treat to bridges. When it is not directly measured, it can be very difficult to detect and may go unnoticed until it produces catastrophic effects. Thus, understanding the effects of scour on bridge structures is of paramount importance for the development of effective scour monitoring strategies and early warning scour systems. This paper investigates the impact of scour on masonry arch bridges, which are the bridge typology most vulnerable to such a hazard. It aims at identifying synthetic damage parameters that can be used for bridge vulnerability and risk assessment, as well as at providing information about the optimal sensor placement in a monitoring system. For this purpose, extensive numerical analyse...