The paper is devoted to the study of topologies on the group $\text{\rm Aut}(X,{\Cal B})$ of all Borel automorphisms of a standard Borel space $(X, {\mathcal B})$. Several topologies are introduced and all possible relations between them are found. One of these topologies, $\tau$, is a direct analogue of the uniform topology widely used in ergodic theory. We consider the most natural subsets of $\text{\rm Aut}(X,{\mathcal B})$ and find their closures. In particular, we describe closures of subsets formed by odometers, periodic, aperiodic, incompressible, and smooth automorphisms with respect to the defined topologies. It is proved that the set of periodic Borel automorphisms is dense in $\text{\rm Aut}(X,{\mathcal B})$ (Rokhlin lemma) with ...