Climate simulation and projections using regional climate models (RCMs) are sensitive to the choice of lateral boundary conditions (LBCs) which often are derived from global climate models (GCM). These LBCs used to drive RCMs describe the atmospheric conditions at the boundaries regarding atmospheric dynamics as well as atmospheric physics, including wind, atmospheric pressure, temperature and humidity. Understanding the impact of each component of LBCs is important for understanding and reducing the uncertainty in and improving the accuracy of RCM climate simulations and projections. In this study, the ICTP Regional Climate Model Version 4 (RegCM4) is used to investigate the impact of LBC on projected future changes of regional climate in ...