Molecular signatures in the progression of COVID-19 severity

Authors of the article discuss that to uncover genes and pathways involved in the differential clinical manifestations of COVID-19 they developed a novel gene co-expression network-based pipeline that uses gene expression obtained from different SARS-CoV-2 infected human tissues. Their study shines a new light on genes and their networks (modules) that drive the progression of COVID-19 from moderate to extremely severe condition, which could aid development of new therapeutics to combat COVID-19