Same experiment as in Fig 3, but in a transgenic background that also expresses Chrimson in the mechanosensory neurons. Results are consistent with Fig 3. Worm spent more time reversing when the RIV, SMB, and SAA neurons were inhibited compared to when a control stimulus intensity was used. Error bars represent 95% confidence intervals; *** indicates pp value is listed in S1 Table. The number of stimulus events for mock and experimental conditions are 1,168 and 1,364, respectively. The number of assays was N = 12. All data underlying this figure can be found at https://doi.org/10.25452/figshare.plus.23903202. (EPS)</p
<p>(A) Example recordings from SST-PC and PV-PC pairs. PC and PV neurons showed no spontaneous activ...
<p>(A) The number of AV in neurites decreased significantly in neurons exposed to the SIV-infected m...
<p><b>(A-D)</b> Heat maps (A, B, D) and the average turning angle (C) for the SMDD- or SMDV-ablated ...
Neurons RIV, SMB, and SAA were optogenetically inhibited when worms spontaneously reversed. The time...
(A) Animals expressing Chrimson in their gentle-touch mechanosensory neurons were optogenetically st...
Probability of reversals when touch neurons are activated or when touch neurons are activated and RI...
(A) Probability of reversals when either touch neurons are activated, or RIV, SMB, and SAA are inhib...
(A) Closed-loop optogenetic stimulation is delivered to animals as they crawl based on their current...
Probability of evoked reversal in response to optogenetic stimulation to gentle-touch mechanosensory...
(A) Anatomical connectivity showing chemical (arrows) and electrical (resistor symbol) synapses amon...
Animals express the inhibitory opsin gtACR2 in RIV, SMB, and SAA and the excitatory opsin Chrimson i...
<p>(A–B) Representative traces of fictive motor activity recorded on the same side of the spinalized...
Animals must integrate sensory cues with their current behavioral context to generate a suitable res...
vFMCx. (a and b) PSTHs of an example layer 6 (L-6) neuron in S1. Activity is shown for the total du...
<p>Synchronized L1 P<i>gcy-8</i>::GFP transgene larvae were incubated with 0.01 µM of Se(IV) or dist...
<p>(A) Example recordings from SST-PC and PV-PC pairs. PC and PV neurons showed no spontaneous activ...
<p>(A) The number of AV in neurites decreased significantly in neurons exposed to the SIV-infected m...
<p><b>(A-D)</b> Heat maps (A, B, D) and the average turning angle (C) for the SMDD- or SMDV-ablated ...
Neurons RIV, SMB, and SAA were optogenetically inhibited when worms spontaneously reversed. The time...
(A) Animals expressing Chrimson in their gentle-touch mechanosensory neurons were optogenetically st...
Probability of reversals when touch neurons are activated or when touch neurons are activated and RI...
(A) Probability of reversals when either touch neurons are activated, or RIV, SMB, and SAA are inhib...
(A) Closed-loop optogenetic stimulation is delivered to animals as they crawl based on their current...
Probability of evoked reversal in response to optogenetic stimulation to gentle-touch mechanosensory...
(A) Anatomical connectivity showing chemical (arrows) and electrical (resistor symbol) synapses amon...
Animals express the inhibitory opsin gtACR2 in RIV, SMB, and SAA and the excitatory opsin Chrimson i...
<p>(A–B) Representative traces of fictive motor activity recorded on the same side of the spinalized...
Animals must integrate sensory cues with their current behavioral context to generate a suitable res...
vFMCx. (a and b) PSTHs of an example layer 6 (L-6) neuron in S1. Activity is shown for the total du...
<p>Synchronized L1 P<i>gcy-8</i>::GFP transgene larvae were incubated with 0.01 µM of Se(IV) or dist...
<p>(A) Example recordings from SST-PC and PV-PC pairs. PC and PV neurons showed no spontaneous activ...
<p>(A) The number of AV in neurites decreased significantly in neurons exposed to the SIV-infected m...
<p><b>(A-D)</b> Heat maps (A, B, D) and the average turning angle (C) for the SMDD- or SMDV-ablated ...