These are the complete summary statistics for DIRECT genotype-phenotypes associations (QTLs). The project performed genotype-phenotype associations for gene expression (RNAseq), targeted proteins (Olink), targeted metabolites (Biocrates) and untargeted metabolites (Metabolon) derived from 3,029 blood and plasma samples from the DIRECT cohort. This submission includes supplementary files and nominal pvalues (as uncorrected pvalues) for all associations included in the manuscript. Trans associations included are typically limited to pvalues <1e-04. Network tables are also included, with information to load and use Cytoscape to visualize them. This is version 2, some files were missing on version 1
<p>Results of the haplotype association analysis for the common QTL regions in the merged dataset an...
Residual bone and fecundity phenotypes (adjusted for body weight), preprocessed gene expression data...
R/qtl is free and powerful software for mapping and exploring quantitative trait loci (QTL). R/qtl p...
These are the complete summary statistics for DIRECT genotype-phenotypes associations (QTLs). The pr...
Description of the different phenotypic datasets used for QTL validation through genomewide associat...
<p>Summary of derived alleles from QTL and GWAS variants: A. Types of nucleotide substitutions; B. D...
Expression quantitative trait loci (eQTLs) are genetic markers associated with transcription of Ribo...
Full summary statistics of all the cis-QTL mapping results presented in the i2QTL manuscript: System...
Data relevant to Wu et al. "Joint analysis of GWAS and multi-omics QTL summary statistics reveals a ...
Although the term quantitative trait locus (QTL) strictly refers merely to a genetic variant that ca...
In this file, genotypic data for QTL analyses of the three crosses are given. Format of these data f...
<p>Summary of significant association between GWAS discovered variant genotypes and mRNA gene expres...
The archive contains 6 files corresponding to genotypic and phenotypic data for the QTL mapping. Eac...
R/qtl is free and powerful software for mapping and exploring quantitative trait loci (QTL). R/qtl p...
Additional file 2. Summary statistics of meQTL replication results for selected CpG sites using MeDI...
<p>Results of the haplotype association analysis for the common QTL regions in the merged dataset an...
Residual bone and fecundity phenotypes (adjusted for body weight), preprocessed gene expression data...
R/qtl is free and powerful software for mapping and exploring quantitative trait loci (QTL). R/qtl p...
These are the complete summary statistics for DIRECT genotype-phenotypes associations (QTLs). The pr...
Description of the different phenotypic datasets used for QTL validation through genomewide associat...
<p>Summary of derived alleles from QTL and GWAS variants: A. Types of nucleotide substitutions; B. D...
Expression quantitative trait loci (eQTLs) are genetic markers associated with transcription of Ribo...
Full summary statistics of all the cis-QTL mapping results presented in the i2QTL manuscript: System...
Data relevant to Wu et al. "Joint analysis of GWAS and multi-omics QTL summary statistics reveals a ...
Although the term quantitative trait locus (QTL) strictly refers merely to a genetic variant that ca...
In this file, genotypic data for QTL analyses of the three crosses are given. Format of these data f...
<p>Summary of significant association between GWAS discovered variant genotypes and mRNA gene expres...
The archive contains 6 files corresponding to genotypic and phenotypic data for the QTL mapping. Eac...
R/qtl is free and powerful software for mapping and exploring quantitative trait loci (QTL). R/qtl p...
Additional file 2. Summary statistics of meQTL replication results for selected CpG sites using MeDI...
<p>Results of the haplotype association analysis for the common QTL regions in the merged dataset an...
Residual bone and fecundity phenotypes (adjusted for body weight), preprocessed gene expression data...
R/qtl is free and powerful software for mapping and exploring quantitative trait loci (QTL). R/qtl p...