These are the complete summary statistics for DIRECT genotype-phenotypes associations (QTLs). The project performed genotype-phenotype associations for gene expression (RNAseq), targeted proteins (Olink), targeted metabolites (Biocrates) and untargeted metabolites (Metabolon) derived from 3,029 blood and plasma samples from the DIRECT cohort. This submission includes supplementary files and nominal pvalues (as uncorrected pvalues) for all associations included in the manuscript. Trans associations included are typically limited to pvalues <1e-04. Network tables are also included, with information to load and use Cytoscape to visualize them
R/qtl is free and powerful software for mapping and exploring quantitative trait loci (QTL). R/qtl p...
This dataset contains eQTL summary statistics for all SNPs-gene pairs in 8 major brain cell types (w...
Residual bone and fecundity phenotypes (adjusted for body weight), preprocessed gene expression data...
These are the complete summary statistics for DIRECT genotype-phenotypes associations (QTLs). The pr...
Expression quantitative trait loci (eQTLs) are genetic markers associated with transcription of Ribo...
Although the term quantitative trait locus (QTL) strictly refers merely to a genetic variant that ca...
Full summary statistics of all the cis-QTL mapping results presented in the i2QTL manuscript: System...
Data relevant to Wu et al. "Joint analysis of GWAS and multi-omics QTL summary statistics reveals a ...
<p>Results of the haplotype association analysis for the common QTL regions in the merged dataset an...
<p>Summary of derived alleles from QTL and GWAS variants: A. Types of nucleotide substitutions; B. D...
<p>(A) Association results for genotyped SNPs. SNPs with <i>P</i>-values achieving genome-wide signi...
Description of the different phenotypic datasets used for QTL validation through genomewide associat...
<p>Table displays significant associations of eQTL genes and metabolites for validated loci. Genes a...
<p>Summary of significant association between GWAS discovered variant genotypes and mRNA gene expres...
We applied a range of genome-wide association (GWA) methods to map quantitative trait loci (QTL) in ...
R/qtl is free and powerful software for mapping and exploring quantitative trait loci (QTL). R/qtl p...
This dataset contains eQTL summary statistics for all SNPs-gene pairs in 8 major brain cell types (w...
Residual bone and fecundity phenotypes (adjusted for body weight), preprocessed gene expression data...
These are the complete summary statistics for DIRECT genotype-phenotypes associations (QTLs). The pr...
Expression quantitative trait loci (eQTLs) are genetic markers associated with transcription of Ribo...
Although the term quantitative trait locus (QTL) strictly refers merely to a genetic variant that ca...
Full summary statistics of all the cis-QTL mapping results presented in the i2QTL manuscript: System...
Data relevant to Wu et al. "Joint analysis of GWAS and multi-omics QTL summary statistics reveals a ...
<p>Results of the haplotype association analysis for the common QTL regions in the merged dataset an...
<p>Summary of derived alleles from QTL and GWAS variants: A. Types of nucleotide substitutions; B. D...
<p>(A) Association results for genotyped SNPs. SNPs with <i>P</i>-values achieving genome-wide signi...
Description of the different phenotypic datasets used for QTL validation through genomewide associat...
<p>Table displays significant associations of eQTL genes and metabolites for validated loci. Genes a...
<p>Summary of significant association between GWAS discovered variant genotypes and mRNA gene expres...
We applied a range of genome-wide association (GWA) methods to map quantitative trait loci (QTL) in ...
R/qtl is free and powerful software for mapping and exploring quantitative trait loci (QTL). R/qtl p...
This dataset contains eQTL summary statistics for all SNPs-gene pairs in 8 major brain cell types (w...
Residual bone and fecundity phenotypes (adjusted for body weight), preprocessed gene expression data...