Screening Compounds of Interest against USP5 Zf-UBD by SPR #2

Determination of binding affinities of compounds of interest previously identified in a 19F-NMR spectroscopy assay against USP5 zinc finger ubiquitin binding domain (Zf-UBD) with a surface plasmon resonance (SPR) assayFunding Acknowledgment: The SGC is a registered charity (number 1097737) that receives funds from AbbVie, Bayer Pharma AG, Boehringer Ingelheim, Canada Foundation for Innovation, Eshelman Institute for Innovation, Genome Canada through Ontario Genomics Institute [OGI-055], Innovative Medicines Initiative (EU/EFPIA) [ULTRA-DD grant no. 115766], Janssen, Merck KGaA, Darmstadt, Germany, MSD, Novartis Pharma AG, Ontario Ministry of Research, Innovation and Science (MRIS), Pfizer, São Paulo Research Foundation-FAPESP, Takeda, and Wellcome