***NOTE: An updated version of this dataset is available at https://zenodo.org/record/46746#.VtW7MmSAOko Different simulation scenarios on which to test cell type adjustment methods for epigenome-wide association studies. Each .RData file contains a matrix of methylation beta-values from a simulated blood cell mixture "sim_beta", a list of simulated differentially methylated positions "dmr", and a phenotype "disease_status"
<p>(A) Simulation DNA methylation level distribution of two samples. (C) Distribution of absolute di...
[[abstract]]Background: High throughput methods such as microarray and DNA-methylation are used to m...
The potential influence of underlying differences in relative leukocyte distributions in studies inv...
<p>***NOTE: An updated version of this dataset is available at https://zenodo.org/record/46746#.VtW7...
<p>Different simulation scenarios on which to test cell type adjustment methods for epigenome-wide a...
Background: Many different methods exist to adjust for variability in cell-type mixture proportions ...
Technological advances and reduced costs of high-density methylation arrays have led to an increasin...
Motivation: Recently there has been increasing interest in the effects of cell mixture on the measur...
This thesis developed statistical methods for investigating chemical changes at the level of the hum...
Abstract Background Whole blood is frequently utilized in genome-wide association studies of DNA met...
This is the R package associated with the work "CeDAR: incorporating cell type hierarchy improves ce...
Based on an extensive simulation study, McGregor and colleagues recently recommended the use of surr...
Simulated data used in the driverMAPS paper: Zhao, S. et al. Model-based analysis of positive sele...
Simulated data used in the driverMAPS paper: Zhao, S. et al. Model-based analysis of positive sele...
We performed systematic assessment of computational deconvolution methods that play an important rol...
<p>(A) Simulation DNA methylation level distribution of two samples. (C) Distribution of absolute di...
[[abstract]]Background: High throughput methods such as microarray and DNA-methylation are used to m...
The potential influence of underlying differences in relative leukocyte distributions in studies inv...
<p>***NOTE: An updated version of this dataset is available at https://zenodo.org/record/46746#.VtW7...
<p>Different simulation scenarios on which to test cell type adjustment methods for epigenome-wide a...
Background: Many different methods exist to adjust for variability in cell-type mixture proportions ...
Technological advances and reduced costs of high-density methylation arrays have led to an increasin...
Motivation: Recently there has been increasing interest in the effects of cell mixture on the measur...
This thesis developed statistical methods for investigating chemical changes at the level of the hum...
Abstract Background Whole blood is frequently utilized in genome-wide association studies of DNA met...
This is the R package associated with the work "CeDAR: incorporating cell type hierarchy improves ce...
Based on an extensive simulation study, McGregor and colleagues recently recommended the use of surr...
Simulated data used in the driverMAPS paper: Zhao, S. et al. Model-based analysis of positive sele...
Simulated data used in the driverMAPS paper: Zhao, S. et al. Model-based analysis of positive sele...
We performed systematic assessment of computational deconvolution methods that play an important rol...
<p>(A) Simulation DNA methylation level distribution of two samples. (C) Distribution of absolute di...
[[abstract]]Background: High throughput methods such as microarray and DNA-methylation are used to m...
The potential influence of underlying differences in relative leukocyte distributions in studies inv...