<p>***NOTE: An updated version of this dataset is available at https://zenodo.org/record/46746#.VtW7MmSAOko</p> <p>Different simulation scenarios on which to test cell type adjustment methods for epigenome-wide association studies. Each .RData file contains a matrix of methylation beta-values from a simulated blood cell mixture "sim_beta", a list of simulated differentially methylated positions "dmr", and a phenotype "disease_status".</p
The potential influence of underlying differences in relative leukocyte distributions in studies inv...
High costs and technical limitations of cell sorting and single-cell techniques currently restrict t...
Background: Association studies of epigenome-wide DNA methylation and disease can inform biological ...
***NOTE: An updated version of this dataset is available at https://zenodo.org/record/46746#.VtW7MmS...
<p>Different simulation scenarios on which to test cell type adjustment methods for epigenome-wide a...
Background: Many different methods exist to adjust for variability in cell-type mixture proportions ...
Technological advances and reduced costs of high-density methylation arrays have led to an increasin...
Abstract Background Whole blood is frequently utilized in genome-wide association studies of DNA met...
This thesis developed statistical methods for investigating chemical changes at the level of the hum...
Motivation: Recently there has been increasing interest in the effects of cell mixture on the measur...
Based on an extensive simulation study, McGregor and colleagues recently recommended the use of surr...
[[abstract]]Background: High throughput methods such as microarray and DNA-methylation are used to m...
This is the R package associated with the work "CeDAR: incorporating cell type hierarchy improves ce...
We performed systematic assessment of computational deconvolution methods that play an important rol...
Posté sur bioRxiv le 30/10/2018DNA methylation is a stable epigenetic alteration that plays a key ro...
The potential influence of underlying differences in relative leukocyte distributions in studies inv...
High costs and technical limitations of cell sorting and single-cell techniques currently restrict t...
Background: Association studies of epigenome-wide DNA methylation and disease can inform biological ...
***NOTE: An updated version of this dataset is available at https://zenodo.org/record/46746#.VtW7MmS...
<p>Different simulation scenarios on which to test cell type adjustment methods for epigenome-wide a...
Background: Many different methods exist to adjust for variability in cell-type mixture proportions ...
Technological advances and reduced costs of high-density methylation arrays have led to an increasin...
Abstract Background Whole blood is frequently utilized in genome-wide association studies of DNA met...
This thesis developed statistical methods for investigating chemical changes at the level of the hum...
Motivation: Recently there has been increasing interest in the effects of cell mixture on the measur...
Based on an extensive simulation study, McGregor and colleagues recently recommended the use of surr...
[[abstract]]Background: High throughput methods such as microarray and DNA-methylation are used to m...
This is the R package associated with the work "CeDAR: incorporating cell type hierarchy improves ce...
We performed systematic assessment of computational deconvolution methods that play an important rol...
Posté sur bioRxiv le 30/10/2018DNA methylation is a stable epigenetic alteration that plays a key ro...
The potential influence of underlying differences in relative leukocyte distributions in studies inv...
High costs and technical limitations of cell sorting and single-cell techniques currently restrict t...
Background: Association studies of epigenome-wide DNA methylation and disease can inform biological ...