Purpose – the purpose of this study is to identify the application of Psychosocial-spiritual in rehabilitation pesantren for people with mental disorders and for former drug addicts as well as to find the strengths and weaknesses of pesantren-based Psychosocial-spiritual.Method – The research method used was qualitative descriptive with the subject of Pondok officials and the students. Data collection was through interviews, observation, and documentation. The research location was in a pesantren specific for people with mental disorders and drug rehabilitation. Data analysis techniques in this research interactive model include data reduction, data presentation, and conclusion.Result - Psychosocial-spiritual therapy is related to some pe...