X-ray crystal structure of a SARS-CoV-2 RBD–Fab ICO-hu23 complex.
- Paule Hermet (15148140)
- Benoît Delache (51391)
- Cecile Herate (564152)
- Esther Wolf (15504248)
- Gaily Kivi (680013)
- Erkki Juronen (290366)
- Karl Mumm (3346817)
- Eva Žusinaite (748845)
- Denis Kainov (775886)
- Eve Sankovski (6704120)
- Kai Virumäe (15148137)
- Anu Planken (547323)
- Andres Merits (191446)
- Jessica E. Besaw (16733957)
- Ai Woon Yee (16733960)
- Takefumi Morizumi (1990708)
- Kyumhyuk Kim (16733963)
- Anling Kuo (3211263)
- Asma Berriche (16733966)
- Nathalie Dereuddre-Bosquet (114584)
- Quentin Sconosciuti (12496852)
- Thibaut Naninck (10319269)
- Francis Relouzat (12496849)
- Mariangela Cavarelli (376532)
- Mart Ustav (373208)
- Derek Wilson (4413649)
- Oliver P. Ernst (141669)
- Andres Männik (454858)
- Roger LeGrand (7375073)
- Mart Ustav Jr. (16733969)
Publication date
August 2023
DOIAbstract
A. The asymmetric unit contains two molecules of RBD (cyan) and two molecules of Fab ICO-hu23 (heavy chain (VH), magenta; light chain (VL), yellow). B. At the RBD–Fab ICO-hu23 interface, Glu-484 of the RBD forms extensive polar interactions with three residues of the Fab ICO-hu23 VH. C Phe-486 of the RBD is surrounded by five aromatic residues, three of VL and two of VH. 2Fo-Fc electron density maps are contoured at 1.5 σ (blue mesh). (TIFF)</p
Add to ORKG