Additional file 4. Summary statistics of Summary-based Mendelian Randomisation with gene expression data. TSV file with the following fields: (1) SMRtest: type of SMR test, can be cis-meQTL, trans-meQTL or target_trans-meQTL. (2) CpG: CpG ID. (3) Gene: ENSEMBL gene ID. (4) SNP: SNP ID in the format of chr:pos, tested for co-localisation. (5–6) chr_cpg, pos_cpg: chromosome and position of CpG. (7) gene_cpg: gene annotated to the CpG. (8–9) chr_snp, pos_snp: chromosome and position of SNP. (10) A1: effect allele. (11) A2: alternative allele. (12) Freq: frequency of A1. (13–15) b_eQTL, se_eQTL, p_eQTL: coefficient estimate, standard error and p-value from the eQTL association. (16–18) b_meQTL, se_meQTL, p_meQTL: coefficient estimate, standard ...
Background: Pinpointing genetic impacts on DNA methylation can improve our understanding of pathways...
Sequencing statistics summary. Table S2. Genome feature association of filtered variant-removed CpGs...
The 3321 probe pairs from the final correlation list. Phenotypic Person correlation and genetic corr...
Additional file 6. Summary statistics of Summary-based Mendelian Randomisation with GWAS data. TSV f...
Additional file 2. Summary statistics of meQTL replication results for selected CpG sites using MeDI...
Additional file 5: Tables S26–S27. Table S26. List of GWASs summary statistics used for the SMR. Tab...
Additional file 1: Supplementary note. Supplementary methods and results, cohort specific acknowledg...
Figure S1. Overview of the EvoImmunoPop experimental setting. Figure S2. Exploring the non-linear ef...
Additional file 7: Figure 3. Proportion difference between random SNPs and SNPs in meQTLs in the Nor...
Additional file 3: Tables S5–S25. Table S5. List of all the enrichment analyses, set of CpGs/SNPs of...
Selected Supplementary Tables - ST5, 7, 8 and 9 Supplementary Table 5. Cosmopolitan results. Cosmop...
Selected Supplementary Tables - ST5, 7, 8 and 9 Supplementary Table 5. Cosmopolitan results. Cosmop...
Figure S4. Comparison of systemic changes of methylome between two samples. (A) Cumulative depth dis...
Item does not contain fulltextINTRODUCTION: An increasing number of studies investigates the influen...
Background: Pinpointing genetic impacts on DNA methylation can improve our understanding of pathways...
Background: Pinpointing genetic impacts on DNA methylation can improve our understanding of pathways...
Sequencing statistics summary. Table S2. Genome feature association of filtered variant-removed CpGs...
The 3321 probe pairs from the final correlation list. Phenotypic Person correlation and genetic corr...
Additional file 6. Summary statistics of Summary-based Mendelian Randomisation with GWAS data. TSV f...
Additional file 2. Summary statistics of meQTL replication results for selected CpG sites using MeDI...
Additional file 5: Tables S26–S27. Table S26. List of GWASs summary statistics used for the SMR. Tab...
Additional file 1: Supplementary note. Supplementary methods and results, cohort specific acknowledg...
Figure S1. Overview of the EvoImmunoPop experimental setting. Figure S2. Exploring the non-linear ef...
Additional file 7: Figure 3. Proportion difference between random SNPs and SNPs in meQTLs in the Nor...
Additional file 3: Tables S5–S25. Table S5. List of all the enrichment analyses, set of CpGs/SNPs of...
Selected Supplementary Tables - ST5, 7, 8 and 9 Supplementary Table 5. Cosmopolitan results. Cosmop...
Selected Supplementary Tables - ST5, 7, 8 and 9 Supplementary Table 5. Cosmopolitan results. Cosmop...
Figure S4. Comparison of systemic changes of methylome between two samples. (A) Cumulative depth dis...
Item does not contain fulltextINTRODUCTION: An increasing number of studies investigates the influen...
Background: Pinpointing genetic impacts on DNA methylation can improve our understanding of pathways...
Background: Pinpointing genetic impacts on DNA methylation can improve our understanding of pathways...
Sequencing statistics summary. Table S2. Genome feature association of filtered variant-removed CpGs...
The 3321 probe pairs from the final correlation list. Phenotypic Person correlation and genetic corr...