(A) The mRNA expression of USP12 were assessed using qPCR analysis in WT mouse BMDMs infected with HSV-1 for indicated time. (B) The protein abundance of USP12 were assessed using western blot in BMDMs infected with infected with HSV-1 for indicated time. (C-D) WT BMDMs were pretreated with NF-κB p65 inhibitor JSH-23 (p65 i), IRF3 inhibitor Geldanamycin (IRF3 i), or STAT1 inhibitor Fludarabine (STAT1 i), and infected with HSV-1 for indicated time. (C) The mRNA expression of USP12 were assessed using qPCR. (D) The protein abundance of USP12 were assessed using western blot. Data shown are the mean ±SD. *P P P (TIF)</p
THP-1-Mφs transfected with transfected with control or expression vector for USP12 were infected wit...
(A) mRNA expression levels of PADI isoforms by RT-qPCR of HSV-1-infected (8 and 16 hpi) vs uninfecte...
(A) mRNA expression levels of PADI isoforms by RT-qPCR of HSV-1-infected (8 and 16 hpi) vs uninfecte...
(A) The mRNA expression of USP12 were assessed using qPCR analysis in THP-1-Mφs infected with HSV-1 ...
THP1-Mφ cells were transfected with control or expression vector for V5-USP12 or V5-USP12C48A, and i...
WT or Usp12-/- BMDMs transfected with control or expression vector for USP12 were infected with VSV ...
WT and Usp12-/- mice were infected with HSV-1 virus (1 × 107 PFU per mouse). (A) Survival rate of WT...
(A) WT BMDMs were infected HSV-1 for 6 hours followed by immunoprecipitation (IP) using anti-UAF1 or...
WT or Usp12-/- BMDMs were infected with VSV, SEV, HSV-1 or CMV, or transfected with Poly (I:C) or Po...
WT and Usp12-/- BMDMs were infected with HSV-1 (A) or VSV (B) at indicated times follow by western b...
WT or Usp12-/- MEFs were infected with VSV, SEV, HSV-1 or CMV, or transfected with Poly (I:C) or Pol...
(A, B) qRT-PCR analysis of Ifnb, Ifna4, Ifnan and Ccl5 mRNA (A), and ELISA analysis of IFN-β, Ccl5 (...
(A) WT, Usp12-/-, Ifi16-/- and Usp12-/-Ifi16-/- BMDMs were infected with HSV-1 for 24 hours, and exp...
(A) qRT-PCR analysis of Ifnb, Ifna4, lfnan and Il6 mRNA in Usp49+/+ and Usp49-/- MLFs (upper), BMDCs...
WT and Usp12-/- mice were infected with VSV virus (1 × 107 PFU per mouse). (A) Survival rate of WT a...
THP-1-Mφs transfected with transfected with control or expression vector for USP12 were infected wit...
(A) mRNA expression levels of PADI isoforms by RT-qPCR of HSV-1-infected (8 and 16 hpi) vs uninfecte...
(A) mRNA expression levels of PADI isoforms by RT-qPCR of HSV-1-infected (8 and 16 hpi) vs uninfecte...
(A) The mRNA expression of USP12 were assessed using qPCR analysis in THP-1-Mφs infected with HSV-1 ...
THP1-Mφ cells were transfected with control or expression vector for V5-USP12 or V5-USP12C48A, and i...
WT or Usp12-/- BMDMs transfected with control or expression vector for USP12 were infected with VSV ...
WT and Usp12-/- mice were infected with HSV-1 virus (1 × 107 PFU per mouse). (A) Survival rate of WT...
(A) WT BMDMs were infected HSV-1 for 6 hours followed by immunoprecipitation (IP) using anti-UAF1 or...
WT or Usp12-/- BMDMs were infected with VSV, SEV, HSV-1 or CMV, or transfected with Poly (I:C) or Po...
WT and Usp12-/- BMDMs were infected with HSV-1 (A) or VSV (B) at indicated times follow by western b...
WT or Usp12-/- MEFs were infected with VSV, SEV, HSV-1 or CMV, or transfected with Poly (I:C) or Pol...
(A, B) qRT-PCR analysis of Ifnb, Ifna4, Ifnan and Ccl5 mRNA (A), and ELISA analysis of IFN-β, Ccl5 (...
(A) WT, Usp12-/-, Ifi16-/- and Usp12-/-Ifi16-/- BMDMs were infected with HSV-1 for 24 hours, and exp...
(A) qRT-PCR analysis of Ifnb, Ifna4, lfnan and Il6 mRNA in Usp49+/+ and Usp49-/- MLFs (upper), BMDCs...
WT and Usp12-/- mice were infected with VSV virus (1 × 107 PFU per mouse). (A) Survival rate of WT a...
THP-1-Mφs transfected with transfected with control or expression vector for USP12 were infected wit...
(A) mRNA expression levels of PADI isoforms by RT-qPCR of HSV-1-infected (8 and 16 hpi) vs uninfecte...
(A) mRNA expression levels of PADI isoforms by RT-qPCR of HSV-1-infected (8 and 16 hpi) vs uninfecte...