This thesis explores the role of the media and communication in the politics of the HIV/AIDS pandemic and the campaign for access to medicines in the Global South. It consists, firstly, of a comprehensive frame analysis of 'AIDS in Africa' in British (Guardian, Daily Mail, BBC News/Newsnight) and pan-European elite news media (Financial Times, The Economist, European Voice) since the late 1980s. It shows that for much of the past two decades the dominant framing is a crisis whose origins are spatially localised within Africa itself, a 'fact of life' of an innately disease-ridden continent. In the early 2000s, as focus shifted to the North-South confrontation over treatment access, a transnational civil society movement succeeded in rupturin...