The traditional configurations of market response, make-to-order (MTO) and make-to-stock (MTS), are no more suitable in today’s competitive context, forcing companies to a transition towards hybrid solutions. Unfortunately, this has been neglected, in particular at the operational level where the Order Review and Release issue counts only two related articles but restricted to job shops. Therefore, researchers are moving towards flow shop configuration, particularly addressing the issue of bottleneck. Literature links this topic to the Theory of Constraints by Goldratt and Cox [14], from which Drum Buffer Rope (DBR) has been designed as a production planning and control tool. The objective of this paper has been defined as verifying how the...