Department of Human Biology, Maastricht University, The Netherlands.OBJECTIVE: Evaluation of motion sensors, specifically accelerometers, as an objective tool for the assessment of physical activity in large populations, over periods long enough to be representative of normal daily life and with minimal discomfort to the subjects. METHOD: Review of validation studies of accelerometers with indirect calorimetry as a reference method. Accelerometers were commercially available one-axial accelerometers: Caltrac, Computer Science Application (CSA) accelerometer, Mini Motionlogger Actigraph; the tri-axial accelerometer Tritrac-R3 D; and an tri-axial accelerometer for movement registration (Tracmor) from our laboratory. RESULTS: There is no clear...