1-Isocyanomethylbenzotriazole and 2,2,4,4-tetramethylbutylisocyanide-cleavable isocyanides useful for the preparation of α-aminomethyl tetrazoles

Dömling, Alexander
Beck, Barbara
Magnin-Lachaux, Marina

Publication date

June 2006

DOI

10.1016/j.tetlet.2006.04.026

Abstract

1-Isocyanomethylbenzotriazole and 2,2,4,4-tetramethylbutylisocyanide smoothly undergo Ugi type reaction toward 1,5-disubstituted aminomethyl tetrazoles and can be subsequently cleaved under acidic conditions yielding substituted α-aminomethyl tetrazoles. © 2006 Elsevier Ltd. All rights reserved

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1-Isocyanomethylbenzotriazole and 2,2,4,4-tetramethylbutylisocyanide-cleavable isocyanides useful for the preparation of α-aminomethyl tetrazoles

Abstract

Extracted data

1-Isocyanomethylbenzotriazole and 2,2,4,4-tetramethylbutylisocyanide-cleavable isocyanides useful for the preparation of α-aminomethyl tetrazoles

Abstract

Extracted data

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