1 The nature of the beta-adrenoceptor(s) mediating adenylyl cyclase activation in rat adipocyte ghosts by (-)-isoprenaline and the lipolytically selective beta-adrenoceptor agonist, BRL 37344, was investigated by use of the beta1-selective antagonist, CGP 20712A. The results were compared with lipolysis in adipocytes.2 While in lipolysis BRL 37344 was a full and 10 times more potent agonist than (-)-isoprenaline, in adenylyl cyclase activation similar pD2 values for both agonists were found. BRL 37344 was only a partial agonist on rat adipocyte adenylyl cyclase, with an intrinsic activity of 0.62.3 With CGP 20712A small rightward shifts of the (-)-isoprenaline concentration-response curve (CRC) were observed at concentrations up to 10-mu-M,...
The pharmacology of the rat adipocyte beta-adrenoceptor has been examined using radioligand binding ...
The beta-adrenoceptor subtypes which trigger lipolysis in white adipocytes vary markedly between cal...
The beta-adrenoceptor subtypes which trigger lipolysis in white adipocytes vary markedly between cal...
1 The nature of the beta-adrenoceptor(s) mediating adenylyl cyclase activation in rat adipocyte ghos...
1 The nature of the beta-adrenoceptor(s) mediating adenylyl cyclase activation in rat adipocyte ghos...
Triglyceride mobilization and adenylyl cyclase activation in adipocytes from Wistar rats, lean Zucke...
Triglyceride mobilization and adenylyl cyclase activation in adipocytes from Wistar rats, lean Zucke...
Triglyceride mobilization and adenylyl cyclase activation in adipocytes from Wistar rats, lean Zucke...
Triglyceride mobilization and adenylyl cyclase activation in adipocytes from Wistar rats, lean Zucke...
A number of catecholamine and non-catecholamine beta-adrenoceptor agonists, including the lipolytica...
A number of catecholamine and non-catecholamine beta-adrenoceptor agonists, including the lipolytica...
A number of catecholamine and non-catecholamine beta-adrenoceptor agonists, including the lipolytica...
A number of catecholamine and non-catecholamine beta-adrenoceptor agonists, including the lipolytica...
A number of catecholamine and non-catecholamine beta-adrenoceptor agonists, including the lipolytica...
The pharmacology of the rat adipocyte beta-adrenoceptor has been examined using radioligand binding ...
The pharmacology of the rat adipocyte beta-adrenoceptor has been examined using radioligand binding ...
The beta-adrenoceptor subtypes which trigger lipolysis in white adipocytes vary markedly between cal...
The beta-adrenoceptor subtypes which trigger lipolysis in white adipocytes vary markedly between cal...
1 The nature of the beta-adrenoceptor(s) mediating adenylyl cyclase activation in rat adipocyte ghos...
1 The nature of the beta-adrenoceptor(s) mediating adenylyl cyclase activation in rat adipocyte ghos...
Triglyceride mobilization and adenylyl cyclase activation in adipocytes from Wistar rats, lean Zucke...
Triglyceride mobilization and adenylyl cyclase activation in adipocytes from Wistar rats, lean Zucke...
Triglyceride mobilization and adenylyl cyclase activation in adipocytes from Wistar rats, lean Zucke...
Triglyceride mobilization and adenylyl cyclase activation in adipocytes from Wistar rats, lean Zucke...
A number of catecholamine and non-catecholamine beta-adrenoceptor agonists, including the lipolytica...
A number of catecholamine and non-catecholamine beta-adrenoceptor agonists, including the lipolytica...
A number of catecholamine and non-catecholamine beta-adrenoceptor agonists, including the lipolytica...
A number of catecholamine and non-catecholamine beta-adrenoceptor agonists, including the lipolytica...
A number of catecholamine and non-catecholamine beta-adrenoceptor agonists, including the lipolytica...
The pharmacology of the rat adipocyte beta-adrenoceptor has been examined using radioligand binding ...
The pharmacology of the rat adipocyte beta-adrenoceptor has been examined using radioligand binding ...
The beta-adrenoceptor subtypes which trigger lipolysis in white adipocytes vary markedly between cal...
The beta-adrenoceptor subtypes which trigger lipolysis in white adipocytes vary markedly between cal...