Donald Trump’s populist, nationalist “America First” agenda advocates a transactional, zero-sum, hypercompetitive, and sovereigntist view of US foreign policy, which many scholars and policymakers conclude poses a considerable challenge to multilateralism. We explore the threat America First presents to the international human rights regime as reflected in important institutions and norms. We survey America First policies regarding immigration and refugee norms as well as norms prohibiting torture and war crimes. We examine its position on the UN Human Rights Commission and the International Criminal Court, consider Trump’s sympathies for autocratic governments, and explore the development of the Commission on Unalienable Rights. Finally, w...