This chapter argues that the standard conception of Spinoza as a fellow-traveling mechanical philosopher and proto-scientific naturalist is misleading. It argues, first, that Spinoza’s account of the proper method for the study of nature presented in the Theological-Political Treatise points away from the one commonly associated with the mechanical philosophy. Moreover, throughout his works Spinoza’s views on the very possibility of knowledge of nature are decidedly skeptical. Third, in the seventeenth-century debates over proper methods in the sciences, Spinoza sided with those who criticized the aspirations of the physico-mathematicians like Galileo, Huygens, Wallis, and Wren who thought the application of mathematics to nature was the wa...