Membrane proteins are of broad interest since they constitute a large fraction of the proteome in all organisms, up to 20-30%. They play a crucial role in many cellular processes mediating information flow and molecular transport across otherwise nearly impermeable membranes. Traditional three-dimensional structural analyses of membrane proteins are difficult to perform, which makes studies of other structural aspects important. The topology of an α-helical membrane protein is a two-dimensional description of how the protein is embedded in the membrane and gives valuable information on both structure and function. This thesis is focused on predicting the topology of α-helical membrane proteins and on assessing and improving the prediction a...
1. Why membrane proteins? 2 Many functions 3 Bioinformatics and membrane proteins: is it feasible ...
The first atomic-resolution structure of a membrane protein was solved in 1985. After 25 years and 2...
The first atomic-resolution structure of a membrane protein was solved in 1985. After 25 years and 2...
Membrane proteins are of broad interest since they constitute a large fraction of the proteome in al...
Membrane proteins constitute a large and important class of proteins. They are responsible for many ...
α-helical membrane proteins constitute 20-30% of all proteins in a cell and are involved in many ess...
Membrane proteins are key elements of the cell since they are associated with a variety of very impo...
For current state-of-the-art methods, the prediction of correct topology of membrane proteins has be...
Membrane proteins fulfil a number of tasks in cells, including signalling, cell-cell interaction, an...
Membrane proteins fulfil a number of tasks in cells, including signalling, cell-cell interaction, an...
α-helical membrane proteins comprise about a quarter of all proteins in a cell and carry out a wide ...
α-helical membrane proteins comprise about a quarter of all proteins in a cell and carry out a wide ...
1. Why membrane proteins? 2 Many functions 3 Bioinformatics and membrane proteins: is it feasible to...
1. Why membrane proteins? 2 Many functions 3 Bioinformatics and membrane proteins: is it feasible to...
Membrane proteins comprise around 20-30% of a typical proteome and play crucial roles in a wide vari...
1. Why membrane proteins? 2 Many functions 3 Bioinformatics and membrane proteins: is it feasible ...
The first atomic-resolution structure of a membrane protein was solved in 1985. After 25 years and 2...
The first atomic-resolution structure of a membrane protein was solved in 1985. After 25 years and 2...
Membrane proteins are of broad interest since they constitute a large fraction of the proteome in al...
Membrane proteins constitute a large and important class of proteins. They are responsible for many ...
α-helical membrane proteins constitute 20-30% of all proteins in a cell and are involved in many ess...
Membrane proteins are key elements of the cell since they are associated with a variety of very impo...
For current state-of-the-art methods, the prediction of correct topology of membrane proteins has be...
Membrane proteins fulfil a number of tasks in cells, including signalling, cell-cell interaction, an...
Membrane proteins fulfil a number of tasks in cells, including signalling, cell-cell interaction, an...
α-helical membrane proteins comprise about a quarter of all proteins in a cell and carry out a wide ...
α-helical membrane proteins comprise about a quarter of all proteins in a cell and carry out a wide ...
1. Why membrane proteins? 2 Many functions 3 Bioinformatics and membrane proteins: is it feasible to...
1. Why membrane proteins? 2 Many functions 3 Bioinformatics and membrane proteins: is it feasible to...
Membrane proteins comprise around 20-30% of a typical proteome and play crucial roles in a wide vari...
1. Why membrane proteins? 2 Many functions 3 Bioinformatics and membrane proteins: is it feasible ...
The first atomic-resolution structure of a membrane protein was solved in 1985. After 25 years and 2...
The first atomic-resolution structure of a membrane protein was solved in 1985. After 25 years and 2...