Příprava monoklonálních protilátek specifických proti antigenům viru klíšťové encefalitidy pro další využití v imunodetekci

Monoclonal antibodies are immunoglobulins produced by a single clone of B cells and bind very specifically to a particular antigenic epitope. Hybridoma technology is used for their preparation and they are widely used for the treatment and diagnosis of many diseases. The aim of this study was to prepare monoclonal antibodies specific against tick-borne encephalitis virus antigens for further use in immunodetection, their characterization, and optimization of used detection methods