Supplementary_Material_for_G3-2022-403907_TR1

Reagent Table Figure S1:Source immunoblots for the protein abundances of Figure 3. Figure S2:DNA content profiles of synchronous, elutriated cho2Δ cells. Figure S3:Quantification of histone methylation levels. Figure S4:Source immunoblots for histone methylation levels. Figure S5:Comparison of metabolite levels in haploid wild type cells cultured in different media. Figure S6:Comparison of complex lipid levels in different strains and media. File S1: File with all the loss-of-function phenotypic analyses reported in the literature for genes encoding folate-dependent enzymes and the multiple correspondence analysis (MCA) we performed. File S2:Source data for the graphs in Figures 3, 4, 5, 6, 7, S3, S5. File S3:File with the raw mass spectrometry data for primary metabolites. File S4:File with the raw mass spectrometry data for biogenic amines. File S5:File with the raw mass spectrometry data for complex lipids.