Additional file 1: of Gene-specific DNA methylation profiles and LINE-1 hypomethylation are associated with myocardial infarction risk
- Simonetta Guarrera (136940)
- Giovanni Fiorito (136942)
- N. Onland-Moret (3578753)
- Alessia Russo (300190)
- Claudia Agnoli (115118)
- Alessandra Allione (749744)
- Cornelia Di Gaetano (136935)
- Amalia Mattiello (140078)
- Fulvio Ricceri (300193)
- Paolo Chiodini (586278)
- Silvia Polidoro (151290)
- Graziella Frasca (735672)
- Monique Verschuren (115123)
- Jolanda Boer (3578747)
- Licia Iacoviello (285585)
- Yvonne van der Schouw (3578750)
- Rosario Tumino (43188)
- Paolo Vineis (115119)
- Vittorio Krogh (140072)
- Salvatore Panico (115120)
- Carlotta Sacerdote (140075)
- Giuseppe Matullo (136983)
Publication date
December 2015
DOIAbstract
Supplementary methods. A document with supplementary materials, including the following: (1) subjects: cohort details; lifestyle, anthropometrics, and biochemical measurements; and outcome definition; (2) laboratory methods: EPICOR sample preparation; discovery phase: Illumina Human450K Methylation Assay; replication phase on EPIC-NL sample: Sequenom MassARRAY; and (3) supplementary statistical methods: case-control differential methylation; removal of technical biases; DNA methylation and MI risk; DNA methylation and time to disease (TTD); supplementary references. (DOCX 73 kb
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