Over the last years, deep rolling has been adopted to improve the fatigue strength of railway axles, but very few scientific analyses and studies of this phenomenon are available in the literature. For this reason, the present research investigates some aspects related to the influence of this technological process on fatigue crack growth in railway axles made of EA4T steel grade. Firstly, special full-scale specimens were prepared applying the industrial deep-rolling process. The measurement of the resulting compressive residual stress field was then performed by x-ray diffraction and prompted an experimental crack growth campaign, on small-scale SE(B) and SE(T) specimens, to investigate the behavior of the material at very negative stres...