Pain treatment with high-dose, controlled-release oxycodone: an Italian perspective
- F. Ferrarese
- G. Becchimanzi
- M. Bernardo
- M. A. Conte
- A. Gioia
- D. Ottaviani
- G. Pedelini
- L. Rigotti
- E. Scelzi
- PALOMBA, ROSA
DOIAbstract
To investigate the possible role and tolerability of high-dose (>160 mg/day) oxycodone controlled release (CR) for the treatment of cancer and non-cancer pain. 227 patients with cancer or non-cancer pain were enrolled in an open-label, multi-center, Italian study in order to assess the adequacy of their existing pain management (using a numerical rating scale [NRS]) and the possible benefit high-dose oxycodone CR may offer patients experiencing uncontrolled pain. Results: Pain was poorly controlled at baseline, with only 18.1% of patients reporting adequate pain relief (NRS <3.5). All other patients reported uncontrolled pain, with an average NRS of 7.81. At baseline assessment, 47.89% of patients had been in pain for up to 3 months, 32....
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