Shear behaviour of masonry has been deeply investigated for a lot of masonry types. Nevertheless, there is still a lack of knowledge on the shear response of tuffmasonry, which is widely spread in the existing building inventory in seismic areas like as Italy, Turkey, and Japan. To characterize the non-linear behaviour of the unit–mortar interface within tuffmasonry, a series of directshear tests were carried out. In this paper, both experimental results and empirical formulae are presented. Classical shear strength and deformation parameters along with shearing fracture energy and dilatancy were characterized. A shear response surface including both stress–strain diagrams and the frictional strength model is proposed