Isothermal titration calorimetry (ITC) is a sensitive technique for probing bimolecular processes and can provide direct information about the binding affinity and stoichiometry and the key thermodynamic parameters involved. ITC has been used to investigate the interaction of the ligand H2TMPyP to the two DNA quadruplexes, [d(AGGGT)]4 and [d(TGGGGT)]. Analysis of the ITC data reveals that porphyrin/quadruplex binding stoichiometry under saturating conditions is 1:2 for [d(AGGGT)]4 and 2:1 for [d(TGGGGT)], respectively
G-quadruplexes (GQ) are formed by the association of guanine-rich stretches of DNA. Certain small mo...
The interactions of three related cationic porphyrins, TMPyP4, TMPyP3 and TMPyP2, with a WT 39-mer B...
Interactions of 5,10,15,20-Tetrakis(N-propylpyridinium-4-yl)-21H,23H-porphyrin (TPrPyP4) with dimer ...
Isothermal titration calorimetry (ITC) is a sensitive technique for probing bimolecular processes an...
Isothermal titration calorimetry (ITC) is a sensitive technique for probing bimolecular processes an...
Interactions of 5,10,15,20-Tetrakis(N-methylpyridinium-4-yl)-21H,23H-porphyrin (TMPyP4) and 5,10,15,...
G-quadruplexes are higher-order nucleic acids structures formed by G-rich sequences that are stabili...
AbstractRegulation of the structural equilibrium of G-quadruplex-forming sequences located in the pr...
<p>ITC binding isotherms for titration of PBD ligands (PBD1 and PBD2) with G- quadruplex DNA in 100 ...
G-quadruplex (GQ) structures formed from guanine-rich sequences are found throughout the genome and ...
Thermodynamic studies of ligand binding to hu-man telomere (ht) DNA quadruplexes, as a rule, neglect...
The G-quadruplex (GQ) is a well-studied non-canonical DNA structure formed by G-rich sequences found...
This work studies the binding properties of distamycin and its carbamoyl analog, containing four pyr...
The nature of the binding mode and stoichiometry of the TMPyP4 cationic porphyrin to G-quadruplex st...
AbstractWe completed a biophysical characterization of the c-MYC proto-oncogene P1 promoter quadrupl...
G-quadruplexes (GQ) are formed by the association of guanine-rich stretches of DNA. Certain small mo...
The interactions of three related cationic porphyrins, TMPyP4, TMPyP3 and TMPyP2, with a WT 39-mer B...
Interactions of 5,10,15,20-Tetrakis(N-propylpyridinium-4-yl)-21H,23H-porphyrin (TPrPyP4) with dimer ...
Isothermal titration calorimetry (ITC) is a sensitive technique for probing bimolecular processes an...
Isothermal titration calorimetry (ITC) is a sensitive technique for probing bimolecular processes an...
Interactions of 5,10,15,20-Tetrakis(N-methylpyridinium-4-yl)-21H,23H-porphyrin (TMPyP4) and 5,10,15,...
G-quadruplexes are higher-order nucleic acids structures formed by G-rich sequences that are stabili...
AbstractRegulation of the structural equilibrium of G-quadruplex-forming sequences located in the pr...
<p>ITC binding isotherms for titration of PBD ligands (PBD1 and PBD2) with G- quadruplex DNA in 100 ...
G-quadruplex (GQ) structures formed from guanine-rich sequences are found throughout the genome and ...
Thermodynamic studies of ligand binding to hu-man telomere (ht) DNA quadruplexes, as a rule, neglect...
The G-quadruplex (GQ) is a well-studied non-canonical DNA structure formed by G-rich sequences found...
This work studies the binding properties of distamycin and its carbamoyl analog, containing four pyr...
The nature of the binding mode and stoichiometry of the TMPyP4 cationic porphyrin to G-quadruplex st...
AbstractWe completed a biophysical characterization of the c-MYC proto-oncogene P1 promoter quadrupl...
G-quadruplexes (GQ) are formed by the association of guanine-rich stretches of DNA. Certain small mo...
The interactions of three related cationic porphyrins, TMPyP4, TMPyP3 and TMPyP2, with a WT 39-mer B...
Interactions of 5,10,15,20-Tetrakis(N-propylpyridinium-4-yl)-21H,23H-porphyrin (TPrPyP4) with dimer ...