Multiple linear interferences are a fundamental obstacle in many standard models. This problem appears as a result of linear relationships between two explanatory variables or more. Simulation results show that the generalized Liu regression model was the best and that the contraction parameter proposed was more efficient than the methods presented. As the error variance increases, the value (MSE) increases. When this problem exists in the data, the estimator of the ordinary least squares method will fail because one of the basic assumptions of the method has not been fulfilled. The normal least squares, which state that there is no linear correlation between the explanatory variables, will not get an estimator with the Best Linear Unbiased...